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Old 10-29-2012, 03:51 PM   #1
Jack Yee
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hunger hormones and testosterone/HGH

So, if are hunger hormones like ghrelin goes up, so does are test/HGH level? Is this why fasting is good for building muscles and burning fat?

Thanks all!
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Old 10-29-2012, 04:14 PM   #2
Jesse Martin
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Re: hunger hormones and testosterone/HGH

I highly doubt fasting has any effect on testosterone.
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Old 10-29-2012, 05:27 PM   #3
Michael Dries
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Re: hunger hormones and testosterone/HGH

Berkhan has a long write up on this in a Q&A post. It's quite wordy but interesting.

http://www.leangains.com/2009/08/questions-answers.html
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Old 10-29-2012, 05:32 PM   #4
Matt Sloan
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Re: hunger hormones and testosterone/HGH

Fasting will supposedly tank your t levels and fasting has been show to increase Gh.. if i remember right?
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Old 10-30-2012, 04:15 AM   #5
Bill M. Hesse
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Re: hunger hormones and testosterone/HGH

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Originally Posted by Matt Sloan View Post
Fasting will supposedly tank your t levels and fasting has been show to increase Gh.. if i remember right?
This is correct as far as I can tell.
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Old 11-01-2012, 08:22 AM   #6
Richard Deyan
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Re: hunger hormones and testosterone/HGH

J Clin Endocrinol Metab. 1998 Jun;83(6):1967-75.
Fasting suppresses pulsatile luteinizing hormone (LH) secretion and enhances orderliness of LH release in young but not older men.
Bergendahl M, Aloi JA, Iranmanesh A, Mulligan TM, Veldhuis JD.
Source

Department of Pediatrics, University of Turku, Finland.
Abstract

Pulsatile gonadotropin secretion and sex-steroid concentrations are suppressed reversibly in young fasted or malnourished human subjects. In this study, we investigated the impact of age on the dynamic neuroendocrine mechanisms underlying this stress response in healthy young (age, 28 +/- 3 yr, n = 8) vs. older (age 67 +/- 2 yr, n = 8) men with similar body mass indices (mean, 26 +/- 0.6 vs. 26 +/- 1.3 kg/m2, respectively). Serum LH concentrations were measured by immunoradiometric assay (IRMA) in blood collected at 10-min intervals over 27 h on a control (fed) day and on the third day of a 3.5-day fast (water only) assigned in randomized order. After 24 h of basal sampling, GnRH (10 micrograms i.v. bolus) was administered to test gonadotrope responsiveness. Cortisol, dehydroepiandrosterone sulfate, androstenedione, testosterone, FSH, GH, and PRL were measured in 24-h pooled serum as positive and negative control hormones. Approximate entropy was used to quantitate the orderliness of LH release over 24 h, and a multiple-parameter deconvolution method was applied to quantify pulsatile LH secretion and LH half-life. In the fed state, older men exhibited elevated mean (24-h pooled) serum FSH and cortisol concentrations compared with young controls but equivalent serum LH concentrations and reduced serum GH, free testosterone, androstenedione, and dehydroepiandrosterone sulfate concentrations. Fed older men also manifested a lower frequency and amplitude of 24-h pulsatile LH secretion, and, by approximate entropy calculations, a more disorderly pattern of basal LH release than younger individuals. Three- and one-half days of fasting evoked 40% and 47% increases in mean (24-h) serum cortisol concentrations in young and older men, respectively (P < 0.01 vs. fed, but P = not significant for percentage rise in older vs. young men). Concurrently, fasting induced a 2.1-fold fall in the 24-h endogenous LH production rate in young men (fed 36 +/- 9.7 vs. fasted 17 +/- 2.0 IU/L of distribution volume/day, P < 0.01), but did not significantly affect the daily LH secretion rate in older men (fed 27 +/- 4.5 vs. fasted 21 +/- 3.4 IU/day). The reduced LH production rate in fasting young men was accounted for by a 1.7-fold decline in the mass of LH secreted per burst (fed 2.5 +/- 0.45 vs. fasted 1.5 +/- 0.16 IU/L, P < 0.05), whereas LH burst mass in older men remained unchanged (and low) during fasting. In addition, in young men, during the 3.5-day fast the number of computer-resolved LH secretory bursts per 24 h decreased (fed 15 +/- 0.7 vs. fasted 11 +/- 0.7, P < 0.01), and the interburst interval increased (fed 94 +/- 4.2 vs. fasted 125 +/- 8.7 min, P < 0.05). In contrast, in older men in the fed state, basal LH peak frequency and serum free testosterone concentrations were reduced compared with corresponding values in young men, and did not decline further with fasting. Whereas the orderliness of LH release patterns increased significantly during fasting in the young men, the approximate entropy measure failed to change significantly in unfed older subjects. By cosinor analysis, young men showed lower 24-h mesor (mean of nyctohemeral rhythm of) serum LH concentrations than older volunteers during fasting. Moreover, young but not older men manifested preserved 24-h variations in LH interpulse intervals when fasting. Exogenously stimulated LH release (mean 3-h serum LH concentration or calculated mass of LH secreted) following a single i.v. injection of 10 micrograms GnRH was independent of age and fasting status. We conclude that the metabolic stressor of short-term fasting unmasks specific age-related neuroendocrine contrasts in the stress-responsive control of both the pulsatile and nyctohemeral regulation of the male hypothalamo-pituitary-gonadal-axis.

I don't think there's enough studies on it. The only other human study I found quickly had to do with an overnight fast and I didn't want to list it since I definitely wouldn't consider that IF
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Old 11-03-2012, 08:09 AM   #7
Arturo Garcia
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Re: hunger hormones and testosterone/HGH

Quote:
Originally Posted by Bill M. Hesse View Post
This is correct as far as I can tell.
English is not my first language so please clarify: by "tank", does it mean it "empties" or "lowers" your Test. levels? Or it "fills the tank", as in, it increases it?
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Old 11-03-2012, 10:20 PM   #8
Matt Sloan
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Re: hunger hormones and testosterone/HGH

Quote:
Originally Posted by Arturo Garcia View Post
English is not my first language so please clarify: by "tank", does it mean it "empties" or "lowers" your Test. levels? Or it "fills the tank", as in, it increases it?

Lowers it.
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Old 11-06-2012, 11:52 AM   #9
Arturo Garcia
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Re: hunger hormones and testosterone/HGH

Ok. Is this a proven fact?? The guys who have done IF and post testimonials don't look like they are low on T.... but then again looks are deciving and perhaps things like their libido have turned to crap and one cannot appreciate in photos. Mainly I'm just kinda curious. It lowers Tests. but increases HGH production? Isn't it weird?
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Old 11-07-2012, 09:06 AM   #10
Bill M. Hesse
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Re: hunger hormones and testosterone/HGH

Not really. GH release coincides with hunger hormones and is blunted by the presence of insulin. Thus it seems logical that fasting can increase its release. Lowered T levels I believe are more of a result of under eating, not how often you eat.
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