Copied from Ludwing:
First, this was a PILOT study, not designed for precise estimates of effect size. That any statistically significant difference in energy expenditure was found at all with such limited power represents a remarkable refutation of the null hypothesis (that all calories are alike).
Second, the non-randomized design would almost certainly have introduced bias against the second diet, which in this case was the low carbohydrate diet. Please see my recent rebuttal to Hall's abstract, which very much pertains to the final paper http://*******/1TDKDWI
Full URL as short does not work: https://medium.com/@davidludwigmd/de...257#.d10t1amg2
EDIT: cannot paste short URLs?